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For In Vitro Diagnostic Materials: Efficacy vs. Thimerosal and Sodium Azide
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"For In Vitro Diagnostic Materials: Efficacy vs. Thimerosal and Sodium Azide"

The traditional preservatives used to prevent microbe growth in in vitro diagnostic products are not ideal. Thimerosal, sodium azide, and antibiotics all present challenges.

New preservative materials can eliminate the drawbacks associated with traditional preservatives. Two isothiazolones, the active ingredient in ProCli 150, ProClin 200, ProClin 300, and ProClin 950 preservatives, have a unique mechanism of action that both inhibits bacterial, fungal, and yeast growth and causes cell death. 

This study, conducted by an independent laboratory, compares the antimicrobial efficacy of ProClin 150 preservative, ProClin 300 preservative, sodium azide, and thimerosal in phosphate buffered saline/TWEEN 20 (polysorbate 20). 


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