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"Comparison of Protein Sequencing Analysis of CDNF, IL6, and FGF2 on Platinum and Mass Spectrometry"

Protein sequencing on Platinum offers several advantages for protein identification relative to tandem mass spectrometry, including the convenience of a benchtop sequencer without the need to send samples to a core facility, the simplicity of the workflow without the need for advanced expertise, and the ability to gain deeper insights into the proteome thanks to the information-rich binding signatures of N-terminal amino acid (NAA) recognizers.

This application note from Quantum-Si compares protein sequencing to tandem mass spectrometry for identifying an isolated protein by sequencing the proteins CDNF, FGF2, and IL6 on the Platinum benchtop protein sequencing instrument and analyzing the same proteins by mass spectrometry at a core facility.

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