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Streamlined Target Enrichment and Uniform Sequencing Using xGen Pre-Hybridization Capture Normalase Technology

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"Streamlined Target Enrichment and Uniform Sequencing Using xGen Pre-Hybridization Capture Normalase Technology"

Streamlined target enrichment and uniform sequencing using xGen Pre-Hybridization Capture Normalase technology. In traditional hybrid capture workflows, researchers are required to spend valuable time performing quality control on each library and individually pooling varying volumes to create multi-plex pools for capture.

In traditional hybrid capture workflows, researchers are required to spend valuable time performing quality control on each library and individually pooling varying volumes to create multiplex pools for capture. This method is time consuming, costly, and prone to pooling and pipetting errors.

This scientific paper from IDT shows how a novel enzymatic library normalization technology can outperform alternative methods while enabling high-throughput sample processing with the ability to normalize different library input amounts, and it results in expected variant allele frequencies, ensuring that the process does not interfere with downstream applications.


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