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"NRicher: A Low-Abundance Proteome Enrichment Platform with Seamless Integration of On-Bead Digestion"

For over 10 years, Biotech Support Group has been developing synthetic beads with differential proteome binding properties. Many derivative products are well established in the field with numerous citations in leading journals.

Following BSG’s lead to circumvent immuno-affinity, an approach combining corona-based separations adapted to magnetic nano-particles has been introduced. However, this necessitates a specialized instrument-based workflow, and the need to perform LC-MS analysis on multiple bead-derived sub-proteomes.

This white paper from Biotech Support Group demonstrates how NRicher, a porous bead-based proteomic enrichment platform for LC-MS and functional proteome analysis, can aid in the discovery of low abundance proteins or their modifications as well as targeted quantitative workflows.

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