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Epigenetics & DNA Methylation
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"Epigenetics & DNA Methylation"

This application note is an introductory overview that will provide some background on epigenetic DNA modifications and an overview of recent research that leverages the epigenetic 5-methylcytosine modification in a biosensor to detect DNA methyltransferase (DNMT) activity in tumor cells.

Download this note for an overview on base modifications for epigenetics research:

  • Epigenetic DNA base modifications
  • DNA transformations that affect the presence of 5-methylcytosine (5mC) on DNA
  • Application highlight: Biosensor detection of DNMT activity in tumor cells

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