The RNAscope technology is a novel in situ hybridization method that is designed to detect target RNA in intact cells by using proprietary probes that simultaneously amplify target signal sequences while suppressing background noise from non-specific hybridization.
This technology obviates the need for the costly and time-consuming development of specific antibodies for newly identified gene targets or pathogens such as the SARS-CoV-2 virus. Additionally, the RNAscope technology can be combined with immunohistochemistry on the same slide for detection of RNA and protein simultaneously.
With an ever-growing catalog of probes for over 25,000 targets in 300+ species and the option of made-to-order target probes, the RNAscope technology has become an essential technology for biomarker assessment, featured in over 2,700 publications across multiple different research areas including infectious disease, inflammation, neurobiology, cancer biology, and immuno-oncology.
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