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A New Way of Exploring Immunity--Linking Highly Multiplexed Antigen Recognition to Immune Repertoire and Phenotype
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"A New Way of Exploring Immunity--Linking Highly Multiplexed Antigen Recognition to Immune Repertoire and Phenotype"

We demonstrate the power of the Single Cell Immune Profiling Solution with Feature Barcoding technology

We demonstrate the power of the Single Cell Immune Profiling Solution with Feature Barcoding technology to:

  • Assess the binding specificities of over 150,000 CD8+ T cells from 4 human donors across a highly multiplexed panel of 44 distinct, specific peptide–MHC (pMHC) multimers
  • Uncover data at single cell resolution for gene and cell surface protein expression, TCR-pMHC binding specificity, and paired aß T-cell receptor (TCR) sequences
  • Generate highly multiplexed binding data from many different pMHC multimers in a single experiment
  • Enable the potential to develop novel experimental and analytical approaches
  • Help facilitate a greater understanding of how the adaptive immune system responds to immune insults and contribute to the development of therapeutics


Offered Free by: 10x Genomics
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