Single-cell RNA sequencing (scRNA-Seq) has revolutionized basic and translational research in immunology, developmental biology, and cancer by enabling the resolution of distinct cell populations within heterogeneous samples. The resolution and scale of scRNA-seq are made possible by advances in next-generation sequencing, where greater throughput and faster turnaround times have dramatically reduced the cost of experimentation.
Despite these strengths, there is a growing need for scRNA-seq library preparation technologies that support greater cell throughput and sensitivity with lower background noise. To address these challenges, Parse Bioscience has developed Evercode split-pool combinatorial barcoding to enable scalable scRNA-Seq analysis.
This application note from Singular Genomics highlights the use of the Parse Biosciences Evercode WT kit in combination with the novel G4 Sequencing Platform, demonstrating accuracy and high concordance of the G4 Platform with an industry-leading NGS platform as well as a faster turnaround time.
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