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How to Reduce False Negative SARS-CoV-2 Results with  Silicon Carbide
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"How to Reduce False Negative SARS-CoV-2 Results with Silicon Carbide"

A new comparative study reveals Norgen’s Silicon Carbide-based RNA extraction method is more accurate than the current gold standard, Silica.

Traditional Viral Transport Medias (VTMs) are not ideal for collection or storage of samples for viral detection, as they do not preserve the integrity of the RNA and maintain the infectiousness of the sample. The lack of preservation leads to degradation of RNA, increasing the likelihood of false negative results when using silica-based technologies. The team at Norgen Biotek ran an experiment to compare traditional silica magnetic bead-based technology and silicon carbide-based technology for viral RNA extraction. Read about their innovative technology and results today!


In this blog you will learn:

  • Why it matters if viral RNA is fragmented from VTM storage.
  • Which RNA extraction method resulted in a 25% false negative rate for true positive samples.
  • Why Norgen’s technology can detect positive VTM  samples for days after collection, while a silica-based method may fail.

Offered Free by: Norgen Biotek
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