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Oligonucleotide Deprotection Guide
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"Oligonucleotide Deprotection Guide"

Deprotection is an important step in the oligonucleotide synthesis workflow and can be visualized in three parts: cleavage, phosphate deprotection, and base deprotection.

This guide outlines the various considerations in choosing the optimal deprotection strategy, as well as the variety of options available for deprotection of oligonucleotides.

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