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Publications Utilizing the RNAscope Assay to Validate and Spatially Map Single-cell RNA-Seq Results in the Tissue
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"Publications Utilizing the RNAscope Assay to Validate and Spatially Map Single-cell RNA-Seq Results in the Tissue"

A rapidly increasing number of researchers are publishing in prominent journals using RNAscope assays to spatially map scRNA-Seq results.

Some select publication examples below show how these researchers have been able to:

Spatially map a cell atlas – Molecular architecture of the mouse nervous system, Zeisel, A., et al. (2018). Cell. DOI: 10.1016/j.cell.2018.06.021

Visualize gene signatures of newly identified cell subtypes – Sensory neuron diversity in the inner ear Is shaped by activity, Shrestha, B. R., et al. (2018). Cell. DOI: 10.1016/j.cell.2018.07.007

Classify highly heterogeneous cell types – Molecular diversity and specializations among the cells of adult mouse brain, Saunders, A., et al. (2018). Cell. DOI: 10.1016/j.cell.2018.07.028.

Confirm new therapeutic cell types – A revised airway epithelial hierarchy includes CFTRexpressing ionocytes, Montoro, D. T., et al. (2018). Nature. DOI: 10.1038/s41586-018-0393-7

Characterize the TME and tumor heterogeneity – Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq, Venteicher, A. S., et al. (2017). Science. DOI: 10.1126/science.aai8478

Explore how pathogenic infection affects cellular heterogeneity – Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging, Severo M.S., et al., (2018). PNAS. DOI: 10.1073/pnas.1803062115.

Reveal transcript dynamics and RNA velocity – RNA velocity of single cells, La Manno, G., et al. (2018). Nature. DOI: 10.1038/s41586-018-0414-6

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