In neuroscience research, it is critical to study the complex structure of the different cell types in the brain, as the chemical, morphological, and functional features of brain cell types are extremely diverse.
NanoString’s nCounter Analysis System can look at the expression of up to 800 genes associated with neuropathology and
neuroinflammation. These panels examine and identify five different CNS cell types and 14 different immune cell types to gather a signature profile of biological processes and diseases.
This application note from Canopy Biosciences, a Center of Excellence for NanoString services, describes two recent neuroscience studies using the nCounter platform: one that classifies pediatric ependymomas using custom antibody probes, and another that investigates miRNA expression in microglial-derived extracellular vesicles in Alzheimer’s disease.
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