Research Library

The top resource for free research, white papers, reports, case studies, magazines, and eBooks.

Share Your Content with Us
on TradePub.com for readers like you. LEARN MORE
Transcriptional Profiling of 1.3 Million Brain Cells with the Chromium Single Cell Gene Expression Solution
Request Your Free White Paper Now:

"Transcriptional Profiling of 1.3 Million Brain Cells with the Chromium Single Cell Gene Expression Solution"

High-throughput single cell RNA sequencing (scRNAseq) technologies measure genome-wide transcriptome data at single cell resolution and have revolutionized our ability to study complex biological systems

However, most scRNA-seq technologies can only process hundreds to thousands of cells in a single experiment — far fewer than the number of cells in most tissues and organs. Our understanding of complex biological systems will be fueled by technologies that can process hundreds of thousands to millions of cells at a time.

10x Genomics recently described a fully integrated, droplet-based approach, the Chromium Single Cell Gene Expression Solution, which enables 3’ mRNA digital profiling of hundreds to millions of cells. To demonstrate the scalability of the 10x platform and software, the Chromium Single Cell Gene Expression Solution was used in a study of the mammalian brain, one of the most complex biological systems in nature. Specifically, ~1.3 million brain cells from two embryonic mice were profiled. The single experiment successfully detected major neuronal and non-neuronal cells types and uncovered many substructures within each major subtype, including rare interneurons, without the need for cell enrichment procedures.


Offered Free by: 10x Genomics
See All Resources from: 10x Genomics

Recommended for Professionals Like You:

Thank you

This download should complete shortly. If the resource doesn't automatically download, please, click here.

Thank you

This download should complete shortly. If the resource doesn't automatically download, please, click here.

Thank you

This download should complete shortly. If the resource doesn't automatically download, please, click here.