To understand tumor heterogeneity, tumor microenvironment contexture, and therapeutic response and resistance, researchers need high-resolution views of the cell types and states that drive cancer. Single-cell analysis relies on being able to isolate, dissociate, and suspend living single cells. The sample preparation process is an integral part of the workflow and plays a critical role in data quality.
This whitepaper from 10x Genomics introduces the core concepts and best practices to optimize sample preparation for single-cell research in oncology, providing pertinent protocols, technical notes, video tutorials, and other resources for each step of the sample preparation workflow.
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