Research on ex vivo human cells, including induced pluripotent stem cells and CAR T cells, has advanced remarkably in the last decade, and some cell-based therapies have already been developed. However, much remains to be done to realize the full potential of these therapies.
Key aspects of this research are to ensure that cells are correctly identified, have the correct karyotype and differentiation potential, lack oncogenic mutations, and are free of contaminants. This white paper describes quality control solutions for investigating human cells to establish ex vivo manipulation methods that comply with clinical research.
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