Next-generation sequencing has become a central component of modern microbiome basic and translational research by enabling high-resolution assessment of species diversity and de novo genome assembly at a far lower cost than traditional methods. A key challenge to NGS-based microbiome analysis is the presence of high- and low-GC content organisms, which are traditionally underrepresented in NGS data.
This poster from Singular Genomics evaluates the performance of the novel G4 Sequencing Platform for microbial community analysis by sequencing a National Institute for Standards and Technology microbial reference material.
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