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"How Vendor-Qualified Automated Methods Accelerate NGS Workflows"

With the cost to sequence genomes declining dramatically, scientists and researchers are applying next-generation sequencing (NGS) technology to new discoveries and clinical research applications at a rapidly expanding rate. These applications are driving the need for sample preparation workflows that prepare the DNA/RNA libraries prior to sequencing.

With over 35-years' experience in automated liquid handing, including the Sciclone and Zephyr next-generation sequencing (NGS) workstations, and a pioneer in NGS automation, Revvity has a proven portfolio of automated NGS library preparation solutions.

The increasing appetite for new kits plus the demand for higher-throughput solutions often mean that start-up to sequencing can take months. The development of vendor-qualified, automated library protocols offers a solution to this growing problem.

This scientific brief from Revvity examines how vendor-qualified automated library protocols are shrinking the time laboratories spend to start sequencing from months to days. It also reviews the three steps of library readiness and describes how each one can impact start-up times.

Case studies are also presented that demonstrate the impact of these solutions on NGS application installation and start-up. With at least one vendor offering over 130 of these vendor-qualified automated library protocols, laboratories can now make considerable progress in reducing times to sequencing and data generation.

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