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High-Resolution Detection of DNA Copy Number and Structural Variants with Novel ISH Technology
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"High-Resolution Detection of DNA Copy Number and Structural Variants with Novel ISH Technology"

DNA in situ hybridization (ISH) is a spatial profiling tool based on hybridizing labeled complementary probes to target DNA inside the cell nucleus to visualize any genetic alterations in tissues.

This webinar from ACD discusses how current limitations of DNA in situ hybridization assays are addressed by ACD's novel chromogenic ISH DNAscope Assays, which allow researchers to use a standard bright field microscope to visualize and quantify gene copy number variations and gene rearrangements in tissues with spatial context at single-cell resolution.

Speakers discuss how these novel chromogenic ISH assays are designed to provide:

  • Spatial visualization of any DNA target: Proven “double-Z” probe design and the signal amplification system of RNAscope enables rapid and flexible probe development.
  • Unparalleled performance in detecting small genomic regions and single-gene loci: Amplify target-specific signals, but not background noise from non-specific hybridization.
  • Easy interpretation and high-throughput data analysis.


Offered Free by: ACD
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