Although messenger RNA (mRNA) is the focus of much RNA research, it constitutes a relatively small fraction of total RNA in a cell. Most cellular RNA is ribosomal RNA (rRNA), and removal of this RNA is desirable in many RNA-seq studies to maximize the capacity of the sequencing instrument and reduce costs. There are several methods to achieve this, but rRNA removal methods can be expensive and often require large amounts of RNA as input.
This on-demand webinar from Jumpcode discusses how CRISPRclean technology employs the specificity of CRISPR-Cas9 to degrade selected abundant or biologically uninformative sequences such as ribosomal RNA in prepared next-generation sequencing libraries.
Offered Free by: Jumpcode Genomics
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