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Genome-wide Study Reveals a Pseudogene-Associated Recurrent Gene Fusion in Prostate Cancer
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"Genome-wide Study Reveals a Pseudogene-Associated Recurrent Gene Fusion in Prostate Cancer"

Pseudogenes are a class of non-coding RNA with unknown functions.

While there have been anecdotal observations pseudogene candidates with distinct functional roles, the overall genome-wide expression of pseudogenes in cancer has not reported until recently, with the help of next-generation sequencing technology.

In this webinar, Nallasivam Palanisamy of the Henry Ford Health System will discuss an effort to understand the genome-wide expression of pseudogenes across several solid cancers, which revealed a novel gene fusion involving a pseudogene in prostate cancer.

The objectives of this seminar are:

to present an overview of pseudogene expression in cancer

to discuss a method for the analysis and discovery of cancer-specific pseudogenes

to outline the application of RNA in situ hybridization for the analysis of pseudogenes


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