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Genome-Wide Epigenomic and Transcriptomic Analysis on the Same Cell

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"Genome-Wide Epigenomic and Transcriptomic Analysis on the Same Cell"

Mapping open chromatin regions at the single-cell level elucidates cell-to-cell variability in regulatory landscapes that drives cell fate decisions and responses to stimuli. Assay for transposase-accessible chromatin using sequencing (ATAC-seq) excels at this by providing an unbiased, genome-wide readout of chromatin accessibility with higher sensitivity than its predecessors.

This white paper from BD presents data from studies investigating single-cell epigenomic heterogeneity, gene expression, and gene regulation using BD Rhapsody ATAC-Seq Assays to generate standalone open chromatin profiling data or perform multiomic analyses of open chromatin accessibility and the transcriptome of single cells in a single experiment.


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