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Genetic Classification of Acute Lymphoblastic Leukemia (ALL): RNA Sequencing as an Emerging Clinical Diagnostic Tool
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"Genetic Classification of Acute Lymphoblastic Leukemia (ALL): RNA Sequencing as an Emerging Clinical Diagnostic Tool"

Acute lymphoblastic leukemia (ALL) is a highly heterogenous disease characterized by different genetic alterations of critical importance for a correct clinical diagnosis, disease stratification, disease follow-up, and treatment selection.

ALLs are characterized by gene fusions or display a distinct gene expression signature that can

be used for classification purposes. In this context, RNA-sequencing is becoming an increasingly important diagnostic tool as it can detect gene fusions in an unbiased manner and aid the subtype classification based on distinct gene expression signatures.

This white paper from Qlucore outlines the benefits of RNA-seq for classifying ALL as well as strategies for analyzing RNA-seq data in this context.


Offered Free by: Qlucore
See All Resources from: Qlucore

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