The 10x Genomics Chromium single-cell platform has contributed to basic and translational research in immunology, developmental biology, and cancer by enabling the resolution of distinct cell populations within heterogeneous samples. Single-cell resolution of biological samples has accelerated our understanding of the complexity of living organisms and has opened up new possibilities for research in fields such as cancer research, genomics, and evolutionary biology.
Similarly, next-generation sequencing is an enabling technology for single-cell analysis, providing genomic information about the cell populations. Advancements in NGS over the last decade have contributed to faster, more accurate results while driving down the cost of experiments. The G4 Sequencing Platform combined with the 10x Genomics single-cell analysis platform allows researchers to achieve faster and more flexible sequencing while profiling tens of thousands of cells.
This application note from Singular Genomics demonstrates a workflow for producing data generated using 10x Chromium Single Cell 3’ Gene Expression assay with the novel G4 Sequencing Platform, demonstrating accuracy and technical reproducibility for single-cell analysis.
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