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Dissecting the Cellular and Subcellular Localization of lncRNAs in Lung Cancer with the RNAscope In Situ Hybridization Assay
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"Dissecting the Cellular and Subcellular Localization of lncRNAs in Lung Cancer with the RNAscope In Situ Hybridization Assay"

Traditional methods of detecting proteins in situ in tissues, such as immunohistochemistry (IHC), are not applicable to the visualization of long non-coding RNAs (lncRNA).

However, RNA in situ hybridization via the RNAscope technology can detect lncRNA expression at the single-cell level within its morphological context. Here we present the use of the RNAscope assay to visualize several lncRNAs within the tumor and its relationship to stromal cells.


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