Single cell RNA (scRNA) sequencing is an approach in which cellular RNA is sequenced to profile changes in gene expression during normal development or disease progression.
This approach has broad utility in both basic research disciplines such as immunology, neuroscience, cell and cancer biology, and applied research areas like forensics, agricultural sciences, and infectious diseases.
The data quality is dependent on the starting material, so there is increasing focus on single cell isolation methods that provide highly pure and viable populations of interest.
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