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Advances in Cell and Immunotherapies in Treating Cancer: An Expert Panel Discussion
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"Advances in Cell and Immunotherapies in Treating Cancer: An Expert Panel Discussion"

Cellular and immune therapies in cancer treatment have come a long way in the few decades since the first cDNA piece of the human T-cell receptor gene was cloned in 1984. Now, co-stimulatory and co-inhibitory molecules are being routinely used to modulate T-cell function.

Autologous and allogeneic cancer therapies have moved from experimental trials to clinical settings. Clues to the immunosuppressive tumor environment are being deciphered and deployed in targeted cell and immune therapies. We now have the tools to transform cold tumors — adept at evading the immune system — into hot tumors that are more easily seen by the immune system and targeted with therapies. Personalized therapeutics are enhancing the safety and efficacy of cellular and immune therapy paradigms by selectively targeting malignant tissue. But there is still much to learn.

This white paper from Isoplexis summarizes a panel discussion in which four experts in cellular and immunotherapy for cancer treatment shared their thoughts on the growing demands for cell therapies, the safety of novel therapies, cancer vaccines, and other topics in cell and immunotherapy research.


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