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Accurate LC-MS Bioanalytical Quantification of Itaconic Acid Using the Automated Andrew+ Pipetting Robot for Ostro Sample Preparation
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"Accurate LC-MS Bioanalytical Quantification of Itaconic Acid Using the Automated Andrew+ Pipetting Robot for Ostro Sample Preparation"

This application note from Waters Corporation demonstrates automated sample preparation and protein precipitation extraction of itaconic acid from human plasma for liquid chromatography-mass spectrometry analysis and quantification using the Andrew+ Pipetting Robot with the Waters Ostro 96-well Plate.

When compared to a manual workflow, the Andrew+ had better recoveries and improved RSDs, meeting recommended performance criteria for bioanalytical quantitation assays.


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