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Analysis of circulating nucleic acids in bodily fluids, also known as “liquid biopsy”, is a new and revolutionary development in the world of diagnostics and personalized medicine. Liquid biopsies have rapidly gained prominence with their potential to identify specific biomarkers with a non-invasive sample collection process, diminishing the need for expensive, high-risk, and painful tissue biopsies.

This white paper from Zymo Research outlines next-generation sequencing methods and considerations for liquid biopsy, including sample collection, cell-free DNA isolation, the advantages of epigenetic-based biomarkers, and profiling techniques.

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