Tapestri Platform Resolves Clonality of Heterogeneous Mouse Organoid Cancer Model Through Single-Cell DNA Sequencing of Lentiviral Barcodes Free White Paper

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"Tapestri Platform Resolves Clonality of Heterogeneous Mouse Organoid Cancer Model Through Single-Cell DNA Sequencing of Lentiviral Barcodes"

Free White Paper: "Tapestri Platform Resolves Clonality of Heterogeneous Mouse Organoid Cancer Model Through Single-Cell DNA Sequencing of Lentiviral Barcodes"

Bladder cancer exhibits high genomic heterogeneity, with an average of five mutations or more in the same tumor. Studying diverse higher-order genetic interactions that drive bladder cancer is difficult with current models of tumorigenesis, and it is limited by bulk sequencing which fails to directly discern clonality and resolve mutational co-occurrence patterns.
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