Analysis of the Performance of GMP-Manufactured Cas9 Nucleases for Cell Therapy Applications Free White Paper

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"Analysis of the Performance of GMP-Manufactured Cas9 Nucleases for Cell Therapy Applications"

Free White Paper: "Analysis of the Performance of GMP-Manufactured Cas9 Nucleases for Cell Therapy Applications"

CAR T-cell therapy, first approved by the FDA in 2017, involves the isolation and activation of T cells from a patient’s blood for ex vivo genetic modification, with CRISPR-Cas9 being a widely used nonviral editing tool for this application. The Cas9 nuclease plays a significant role in the performance of the tool and is thus a critical component for therapy development.
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