Copy Number Variants and Single Nucleotide Variants Simultaneously Detected in Single Cells Free White Paper

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"Copy Number Variants and Single Nucleotide Variants Simultaneously Detected in Single Cells"

Free White Paper: "Copy Number Variants and Single Nucleotide Variants Simultaneously Detected in Single Cells"

Cancer begins with mutations in the DNA of a single cell. These mutations are often caused by single nucleotide variants (SNVs) and gene copy number variants (CNVs). Differences in SNVs and CNVs contribute to cancer heterogeneity, making some clonal populations more virulent and drug-resistant than others. Accurately defining clonal populations and reconstructing clonal phylogenies can only be achieved through single-cell analysis and is critical for informed clinical research.
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